Bert Devriendt lab

Prof. dr. Bert Devriendt


Research topic

My team is at the leading edge of research in animal mucosal immunology and host-pathogen interactions with a focus on the development of oral vaccination strategies and novel immune stimulating glycans. We have expertise in evaluating pathogen- and vaccine-induced immune responses, the design and production of recombinant antibodies for the targeted delivery of biologics to the gut tissues and advanced 3D models of the gut epithelium in a variety of animal species.

Selected publications

  1. Van der Weken H et al., 2021. Antibody-Mediated Targeting of Antigens to Intestinal Aminopeptidase N Elicits Gut IgA Responses in Pigs. Front. Immunol. 12:753371. doi: 10.3389/fimmu.2021.753371.
  2. Vermeire B. et al., 2021. Porcine small intestinal organoids as a model to explore ETEC-host interactions in the gut. Vet. Res. 52:94. doi: 10.1186/s13567-021-00961-7.
  3. Hermans L. et al., 2021. ╬▓-Glucan-Induced IL-10 Secretion by Monocytes Triggers Porcine NK Cell Cytotoxicity. Front. Immunol. 12:634402. doi: 10.3389/fimmu.2021.634402.
  4. Wang H. et al., 2020. Porcine Enterotoxigenic Escherichia coli Strains Differ in Their Capacity To Secrete Enterotoxins through Varying YghG Levels. Appl. Environ. Microbiol. 86:e00523-20. doi: 10.1128/AEM.00523-20.
  5. Bakshi S. et al., 2020. Evaluating single-domain antibodies as carriers for targeted vaccine delivery to the small intestinal epithelium. J. Control. Release. 321:416-429. doi: 10.1016/j.jconrel.2020.01.033.

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