Tel: +32 9 33 13 700
Fax: +32 9 221 76 73
The lab of Prof. Libert is focusing on the IECs in systemic acute lethal inflammation (SIRS) and sepsis. They apply several mouse models to trigger SIRS, using TNF, LPS or kidney ischemia/reperfusion, and Cecal Ligation and Puncture to induce sepsis. By means of RNASEQ, electron microscopy and FACS, and with a focus on TNF receptors and glucocorticoids, they zoom iin into the biology of ER stress, cell death, autophagy, but alsos microbiome and metabolism to find new drug targets for sepsis.